Causes of Chest Pain
Sunday, June 14th, 2009The Center for Disease Control estimated in 2005 that chest pain is the second most common complaint in Emergency Departments in the United States and causes about 6 million visits annually. Many emergency room patients presenting the most at-risk and life-threatening type chest pain may appear quite healthy and without extreme distress so determining the cause of chest pain can be extremely critical.
Leading causes of chest pain in ambulatory care include musculoskeletal, gastrointestinal, and pulmonary disorders; as well as a combination of these and psychiatric diagnoses such as panic disorders (PDs). Rarely, life-threatening causes are the source of chest pain in outpatient settings, but must be excluded.
Accute Coronary Syndrome (ACS)
Acute coronary syndrome (ACS) or coronary vascular disease continues to lead the cause of death of adults in developed countries at approximately 10 percent during a 28 day case mortality rate for ACS, but can vary with disease severity and patient treatment received. However, statistics show that:
“less than 15 to 30 percent of patients who present to the emergency department with non-traumatic chest pain have ACS, which includes myocardial infarction and unstable angina.”

always get chest pain checked out
“Chest pain can be a clue to underlying coronary artery disease, but it can also be caused by non-cardiac conditions, most of which are less serious. Proper attention to the quality of the pain and the factors that preceded it can be used as a tool to determine whether the origin is cardiac or not. A stress test is indicated when there is doubt,” reports Peter F. Cohn, MD, Stony Brook University Health Sciences Center in New York.
Two Major Categories of Chest Pain
According to the Mayo Clinic staff, there are two major categories for the causes of chest pain – cardiac and non-cardiac as follows:
Cardiac causes of chest pain may include:
- Heart Attack—blood clot blocks blood flow to heart
- Angina—temporarily restricted blood flow from arteries to your heart
- Other Cardiac Causes—pericarditis (inflammation of the sac surrounding your heart); a rare, life-threatening condition called aortic dissection; and coronary spasm (Prinzmetal’s angina)
- Heart-Related Conditions—metabolic syndrome and endothelial dysfunction.
Non-cardiac causes of chest pain may include:
- Heartburn
- Panic Attacks
- Pleurisy
- Costochondritis
- Pulmonary Embolism
- Other Lung Conditions—collapsed lung (pneumothorax), high blood pressure in the arteries carrying blood to the lungs (pulmonary hypertension) and asthma
- Sore Muscles—chronic pain syndromes
- Injured Ribs or Pinched Nerves
- Swallowing Disorders—painful muscle spasms
- Shingles—produce pain and a band of blisters from back around to chest wall
- Gallbladder or Pancreas Problems— abdominal pain radiates to chest
- Cancer—rarely, may spread from another part of the body
Gender Differences & Chest Pain
Additionally, there are gender differences in the causes of chest pain that should be addressed according to Brenda M. Eden APRN, BC, MS, in “The Nurse Practitioner: The American Journal of Primary Health Care.”
Chest Pain in Women
Chest pain is the cause of 1% (2.9 million) of total visits to primary care clinicians, and is often difficult to diagnose due to variability in symptoms, especially in women. Up to one-half of women with chest pain who undergo coronary angiography do not have coronary artery disease (CAD). In recent years, researchers have explored the differences between men and women in how chest pain is described and reported.
Women are less likely to seek medical care when the symptoms initially present, which delays diagnosis and early intervention. Reasons women delay seeking medical care are related to knowledge deficits, cost, transportation, previous experiences with the healthcare system, perception of pain, fear of not being taken seriously, and self-doubt about the severity of their symptoms.
Although only a limited number of studies have explained a physiologic basis that accounts for gender differences, it is evident that women must be evaluated uniquely. An accurate diagnosis depends on the practitioner’s ability to elicit pertinent information through the patient’s history and physical examination. Algorithms and tools may help determine priority differential diagnoses and appropriate selection of diagnostic tests. Primary care practitioners must integrate gender-specific assessment strategies to successfully treat the underlying cause of chest pain in women.
Whether or not the cause is known, experts agree:
“Patients with chest pain should go immediately to the nearest emergency room, preferably traveling by ambulance. They should not drive themselves. Call 911 or the local emergency number.”
Sources Include
[1] http://www.uptodate.com/patients/content/topic.do?topicKey=~/BLiwvS.f48
[1] http://www.circ.ahajournals.org/cgi/content/full/106/5/530
[1] http://www.mayoclinic.com/health/chest-pain/DS00016/DSECTION=causes
[1] http://www.nursingcenter.com/prodev/cearticleprint.asp?CE_ID=773072
[1] http://www.umm.edu/patiented/articles/how_serious_coronary_artery_disease_000003_2.htm
